A happy medium: the synthesis of medicinally important medium-sized rings via ring expansion
نویسندگان
چکیده
منابع مشابه
Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion
Nature has exploited medium-sized 8- to 11-membered rings in a variety of natural products to address diverse and challenging biological targets. However, owing to the limitations of conventional cyclization-based approaches to medium-ring synthesis, these structures remain severely underrepresented in current probe and drug discovery efforts. To address this problem, we have established an alt...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2020
ISSN: 2041-6520,2041-6539
DOI: 10.1039/d0sc00568a